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Proteomics Research Laboratory

At Wayne State University, we investigate protein signaling, protein-protein interactions, global & phosphoproteomics, and disease mechanisms using state-of-the-art LC-MS/MS and AI-integrated bioinformatics

Proteomics: Inspired By Passion

“Proteomics offers the capability to simultaneously quantify multiple proteins, protein-protein interactions, and protein phosphorylation, providing a better picture of complex protein networks.”

 

Proteomics
Advanced methods in proteomics analyses

Liquid Chromatography
Tailored methods in sample preparation

Bioinformatics
Customized application of proven informatics workflows

Mass Spectrometry
State-of-the-art instrumentation

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Lab Reserach Overview

The mission of our proteomics lab is to provide collaborators the opportunity to take advantage of next-generation mass spectrometers and software platforms to perform TMT-labeled/       label-free quantitative proteomics.

Interactomes

Identifying potential protein interaction partners through characterizing protein interactomes

Post-Translational Modifications

Identifying post-translational modifications (PTMs) and measuring changes in their abundance following cellular treatments, in disease models using cells or animals, as well as in tissue samples from healthy individuals compared to those with disease

Proteomes

Profiling protein abundance changes across entire proteomes, from either cell culture systems, animal models, or human studies